Master 6 questions of penicillin skin test Leave a comment
1, the usual piperacillin sodium sulbactam sodium is a penicillin skin test, but if paper changed the batch number, do you still need to do the skin test?
The skin test was originally done with PG, but it is still done after changing the batch number. Is it meaningful?
Answer: changing batch numbers to do skin tests is part of the hospital regulation, but also the hospital for self-protection and have to do it.
But from the data it is hard to find a basis for the rational use of drugs in recent years and is also specified in the new medicine, penicillin drugs available before the application of skin test of penicillin G sodium solution for a skin test since different drugs can use a skin test, then the different batches of the same drug to replace more no need to proceed to the skin test.
2, our department now penicillin drug skin test is all with penicillin G sodium to do a skin test, such as piperacillin shu Batan sodium, amoxicillin and so on are with penicillin G sodium to do a skin test, I do not know whether it is ok?
Answer: yes, do a skin test with penicillin G sodium, it is to comply with the requirements of drug use instructions and the provisions of Chinese pharmacopeia, it is the legal basis.
3, penicillin drug skin test negative, can rest assured medication?
Answer: the application of penicillin class medicine cannot be careless, make anaphylaxis cure preparation, observe the patient closely.
Patients with negative skin tests should be observed 15 to 30 minutes after the first drug input before leaving, and pay attention to the patient’s complaints, such as numbness, itching, dyspnea, and early detection of allergic reactions, and make corresponding treatment; In the event of anaphylactic shock, every minute counts to save the patient’s life.
4, penicillin drug skin test negative, can rest assured medication?
Answer: the application of penicillin class medicine cannot be careless, make anaphylaxis cure preparation, observe the patient closely.
Patients with negative skin tests should be observed 15 to 30 minutes after the first drug input before leaving, and pay attention to the patient’s complaints, such as numbness, itching, dyspnea, and early detection of allergic reactions, and make corresponding treatment; In the event of anaphylactic shock, every minute counts to save the patient’s life.
5. What should be noted when using penicillin for the first time?
Solution: after injection of penicillin, at least 20 minutes in the hospital observation, no discomfort can be left.
Do not apply penicillin when extreme hunger, in case hollow, when the airframe is opposite medicaments tolerance, is reduced, induce the adverse reaction such as seasickness. When intravenous drip penicillin, the beginning speed does not want too fast, every minute is advisable with do not exceed 40 drops, observe 10, 20 minutes adjust infusion speed again without adverse reaction.
6. What are the common reasons for “false positives” in penicillin skin tests?
Solution: the operation of the intradermal injection is not standard (such as the needle is thick and blunt or the injection is too deep to stimulate the skin, the injection dosage is too much, the skin test solution is placed too long, etc.).
Irritations to the skin caused by disinfectant (when injected intradermally before it dries, the positive result is that the subject is allergic to the disinfectant).
The judgment of the results is not scientific enough (as long as the skin is red or the patient has an unwell chief complaint, it is not analyzed, for fear of risk judgment is positive).
Lack of control means (patients or their families are unwilling to accept the saline control test, lack of scientific basis to exclude false positives).
